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Antidepressant Food Swaps

March 18, 2026by Chris Aiken, MD0
Popcorn, chocolate, nuts, nut-butters, fruit, whole grains, and more healthy snacks

In 2017, researchers discovered a diet that treats depression. The effect was large, comparable to what we see with therapy and medication, and confirmed by independent trials.

The diet encourages people to limit junk foods — those that are fried, fast, sugary, or ultraprocessed — to three small servings a week. That category includes refined “simple” carbs (instead, choose whole grains), sugary drinks, and unhealthy saturated or trans fats.

The OpenFoodFacts app scans bar codes in the grocery store to help you make brain-friendly choices. Here are other simple food swaps to get you started.

Unhealthy food… Swap it for…
Chips Popcorn (stove popped, not microwaved)
Crackers 100% whole wheat crackers or crisp breads
Snacks Celery, carrot, or pepper strips with a dip or nut butter. Fruit. Apples with nut butter (choose a brand with low salt/sugar/processing). Strawberries with goat cheese. Edamame.
Ranch dip Salsa, hummus, chili, baba ghanoush, pesto, balsamic vinegar with extra-virgin olive oil, olive tapenade, almond butter, yogurt dips like tzatziki
Creamy salad dressings Salad dressings made with extra-virgin olive oil, balsamic vinegar, lemon juice, honey, or mustard
Mayonnaise Nayonaise, avacado mayo, mashed avacados, olive oil, mustard
Butter Extra-virgin olive oil
Extra salt Extra herbs, peppers, or spices
Salt cravings Olives, feta cheese, crackers or pretzels made with 100% whole wheat, hummus, pesto, home-made popcorn (popped on the stove, not the microwave), salted nuts, kimchi, dried nori (seaweed) strips. Sprinkle salt in extra-virgin olive oil and dip whole wheat bread in it.
Sugar cravings Healthy fats like nuts, seeds, coconut, olives, hummus, yogurt, avocado, oily fish, tofu, and extra virgin olive oil
Jelly Chopped berries with a dash of honey
Yogurt with sugary fruit Greek or Icelandic (Skyr) yogurt. Start with plain and add berries, nuts, and – only if needed – honey or maple syrup.
Sauces with cheese, cream, or butter Tomato sauce or pesto
Potatoes Sweet, purple, or red potatoes
White rice Brown rice, wild rice, black rice, whole wheat couscous, or quinoa
Pasta 100% whole wheat pasta
Biscuits 100% whole wheat English muffins
White bread 100% whole wheat bread
Deli meats Chicken or turkey breast (these are less processed then packaged slices) or hummus
Hamburgers Bean, veggie, turkey, or salmon burgers
Ice cream Pudding made with skim or 1% milk. Canned pears sprinkled with cinnamon and cocoa nibs. Frozen grapes.
Cookies and candy Nuts and dried berries, dates, and dark chocolate (>70% cocoa)
Coffee creamer Real cream or milk. Even better – almond or soy milk. Artificial creamer is full of trans fats and sugars.
Milk shake Fruit smoothie with nuts and yogurt
Soft drinks Ice tea (unsweetened or sweetened with a little honey)
Sports drinks Coconut water or make your own water by soaking cucumber, mint, citrus, or berries in a pitcher
Energy drinks Green tea
Beer or cocktails No level of alcohol is good for the brain, but red wine is safest (max 5 ounces a day, about ½ metric cup)

—Chris Aiken, MD
Director, Psych Partners
Editor in Chief, Carlat Psychiatry Report

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