BipolarDepressionDifficult to Treat DepressionECTResearchSleepSupplementsMelatonin Protects Memory During ECTJune 2, 2026by Chris Aiken, MD2
BipolarDepressionDifficult to Treat DepressionDisordersMedicationsResearchSide EffectsRisk Factors for Gambling on PramipexoleJune 1, 2026by Chris Aiken, MD0
DepressionDifficult to Treat DepressionInflammationMed-PsychResearchInflammation and Treatment-Resistant DepressionMay 23, 2026by Chris Aiken, MD0
DepressionDifficult to Treat DepressionKetamineMedicationsResearchTherapyPsychotherapy Makes a Difference with EsketamineMay 22, 2026by Chris Aiken, MD0
DepressionDifficult to Treat DepressionKetamineResearchTop ResearchA Drug That Sustains Ketamine’s BenefitsMay 20, 2026by Chris Aiken, MD0
AntidepressantsDepressionDifficult to Treat DepressionKetamineLithiumMedicationsNew Trials Look Long-Term in Treatment-Resistant DepressionMay 20, 2026by Chris Aiken, MD0
AntidepressantsBipolarDepressionDifficult to Treat DepressionKetamineMedicationsPersonality DisordersResearchWho Responds to Ketamine?May 18, 2026by Chris Aiken, MD0
DepressionDifficult to Treat DepressionResearchTherapyIntensive Psychodynamic Therapy for Treatment-Resistant DepressionMay 12, 2026by Chris Aiken, MD0
DepressionDifficult to Treat DepressionKetamineResearchTherapyTop ResearchCBT Helps Sustain EsketamineMay 7, 2026by Chris Aiken, MD0
DepressionDifficult to Treat DepressionKetamineMedicationsResearchEsketamine Over Five Years: Real World DataMay 3, 2026by Chris Aiken, MD0
DepressionDifficult to Treat DepressionMedicationsPsychedelicsResearchTop ResearchPsilocybin in Treatment Resistant DepressionMay 1, 2026by Chris Aiken, MD0
AntidepressantsDepressionDifficult to Treat DepressionLithiumMedicationsResearchLithium, Quetiapine, or Esketamine in Treatment-Resistant Depression?May 1, 2026by Chris Aiken, MD0
DepressionDifficult to Treat DepressionKetamineMedicationsSide EffectsTop ResearchKetamine and Liver Risk: How Worried Should You Be?April 22, 2026by Chris Aiken, MD0
DepressionDifficult to Treat DepressionResearchResearch for the PublicTop ResearchtDCS for Treatment-Resistant DepressionApril 6, 2026by Chris Aiken, MD0
BenzodiazepinesDepressionDifficult to Treat DepressionKetamineMedicationsResearchBenzodiazepines May Blunt EsketamineApril 6, 2026by Chris Aiken, MD1
DepressionDifficult to Treat DepressionResearchTwo Types of Treatment Resistant DepressionMarch 31, 2026by Chris Aiken, MD0
DepressionDifficult to Treat DepressionResearchAn Algorithm for Late-Life DepressionMarch 23, 2026by Chris Aiken, MD0
AntipsychoticsDepressionDifficult to Treat DepressionLithiumResearchTop ResearchQuetiapine vs Lithium for Treatment-Resistant DepressionMarch 23, 2026by Chris Aiken, MD0
DepressionDevicesDifficult to Treat DepressionNeuromodulation/TMSResearchResearch for the PublicTop ResearchA Wearable Headset for Difficult-to-Treat DepressionMarch 15, 2026by Chris Aiken, MD0
AntidepressantsDepressionDifficult to Treat DepressionLithiumMedicationsTop ResearchA New Version of the STAR*D TrialJune 18, 2025by Chris Aiken, MD0